Mohammad A. Vasef - Diagnostic Pathology: Molecular Oncology E-Book

Elsevier

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DIAGNOSTIC PATHOLOGY: MOLECULAR ONCOLOGY, SECOND EDITION

ISBN: 978-0-323-61144-2

Copyright 2020 by Elsevier. All rights reserved.

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Notices

Practitioners and researchers must always rely on their own experience and knowledge in evaluating and using any information, methods, compounds or experiments described herein. Because of rapid advances in the medical sciences, in particular, independent verification of diagnoses and drug dosages should be made. To the fullest extent of the law, no responsibility is assumed by Elsevier, authors, editors or contributors for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation of any methods, products, instructions, or ideas contained in the material herein.

Previous edition copyrighted 2015.

Library of Congress Control Number: 2019941277

The views expressed in this book are those of the author and do not reflect the official policy of the Department of Army/Navy/Air Force, Department of Defense, or U.S. government.

This book reflects the views of the authors and should not be construed to represent the views or policies of the U.S. Food and Drug Administration.

Printed in Canada by Friesens, Altona, Manitoba, Canada

Last digit is the print number: 987654321

To my mother, Shamsi, and my father, Rahim, for their inspiration.

To my dear wife, Fatemeh, and our wonderful children, Yashar and Idean.

To my sisters, Najeebeh and Soudabeh.

Special thanks to Aaron Auerbach for his amazing partnership and contributions, to my colleagues in the Department of Pathology at the University of New Mexico Health Sciences Center, and to Jim Gale and the Molecular Diagnostic Team at TriCore Ref Laboratories.

Thanks,

MAV

This book is dedicated to Suzanne, queen of my heart, and Benjamin and Zachary. Benjamin, you are a great writer and have many books inside you just waiting to be written. Zachary, you are like a superhero, and your power is unlimited energy. Special thanks to Ann, Donald, Shayna, and Jahna, my pillars of support. Mohammad Vasef, thank you for excelling at the art of collaboration; its great to work with you.

AA

Rania Bakkar, MD , Associate Professor of Pathology, Department of Pathology, Cedars Sinai Medical Center, Los Angeles, California

Marc Barry, MD , Associate Professor, Department of Pathology, University of Utah Health Sciences Center, Huntsman Cancer Institute, Salt Lake City, Utah

David Cassarino, MD, PhD , Dermatopathologist, Staff Pathologist, Los Angeles Permanente Medical Center, Los Angeles, California

Joanna L. Conant, MD , Assistant Professor, Department of Pathology and Laboratory Medicine, Robert Larner, M.D. College of Medicine at the University of Vermont, University of Vermont Health Network, Burlington, Vermont

Edgar Fischer, MD, PhD

Staff Pathologist, Pathology Consultants of New Mexico, Roswell, New Mexico

Voluntary Faculty, Department of Pathology, The University of New Mexico Health Sciences Center, Albuquerque, New Mexico

Rama Gullapalli, MD, PhD , Assistant Professor, Department of Pathology, Department of Chemical and Biological Engineering, The University of New Mexico Health Sciences Center, Albuquerque, New Mexico

Joshua Anspach Hanson, MD , Associate Professor, Department of Pathology, The University of New Mexico Health Sciences Center, Albuquerque, New Mexico

David G. Hicks, MD , Professor and Director of IHC-ISH Laboratory and Breast Subspecialty Service, University of Rochester Medical Center, Rochester, New York

Giovanni Insuasti-Beltran, MD , Assistant Professor, Medical Director, Flow Cytometry, Department of Pathology, Wake Forest Baptist Health, Winston-Salem, North Carolina

Nancy Joste, MD , Professor, Department of Pathology, The University of New Mexico Health Sciences Center, Albuquerque, New Mexico

M. Carmen Frias Kletecka, MD , Medical Director, VISN 22 Molecular Diagnostics Laboratory, Pathology & Laboratory Medicine Service, VA Greater Los Angeles Healthcare System, Los Angeles, California

Lesley Lomo, MD , Associate Professor, Department of Pathology, University of Utah Health Sciences Center, Huntsman Cancer Institute, Salt Lake City, Utah

Amer Mahmoud, MD, FCAP

Hematopathology and Molecular Genetic Pathology, Pathology Associates of Albuquerque, PAA, Presbyterian Hospital

Clinical Assistant Professor, Department of Pathology, The University of New Mexico Health Sciences Center, Albuquerque, New Mexico

Samuel Reynolds, MD , Assistant Professor, Department of Pathology, The University of New Mexico Health Sciences Center, Albuquerque, New Mexico

Fausto J. Rodrguez, MD , Associate Professor of Pathology and Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland

Elisabeth Rushing, MD , Institute for Neuropathology, University Hospital of Zurich, Zurich, Switzerland

Von Samedi, MD, PhD , Vice Chair for Education, Associate Professor of Pathology, Director of Residency Program, Director of Cytopathology Fellowship, Department of Pathology, The University of New Mexico Health Sciences Center, Albuquerque, New Mexico