Christine J. Ko - Dermatopathology: Diagnosis by First Impression

To Ulla, Anna, Jessica, and Sara who let me pursue
my career while they took care of everything else. (RJB)

To Peter, Dylan, and Owen. (CJK)

Christine J. Ko

Professor of Dermatology and Pathology
Yale University School of Medicine
New Haven, CT, USA

Ronald J. Barr

Dermatopathologist
Laguna Pathology Medical Group
Laguna Beach, CA
and
Professor Emeritus, Dermatology and Pathology
University of California
Irvine, CA, USA

This edition first published 2017 2017 by John Wiley & Sons, Ltd
First edition 2008 2008 Christine J. Ko and Ronald J. Barr
Second edition 2011 2011 John Wiley & Sons, Ltd

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Library of Congress Cataloging-in-Publication Data

Names: Ko, Christine J., author. | Barr, Ronald J. (Dermatopathologist), author.
Title: Dermatopathology : diagnosis by first impression / Christine J. Ko, Ronald J. Barr.
Description: Third edition. | Oxford, UK ; Ames, Iowa : John Wiley & Sons, Inc., 2017. | Includes indexes.
Identifiers: LCCN 2016016543 (print) | LCCN 2016017183 (ebook) | ISBN 9781119149453 (pbk.) |
ISBN 9781119149460 (pdf) | ISBN 9781119149477 (epub)
Subjects: | MESH: Skin Diseasesdiagnosis | Skin Diseasespathology | Skinpathology | Microscopy | Atlases
Classification: LCC RL96 (print) | LCC RL96 (ebook) | NLM WR 17 | DDC 616.5/075dc23
LC record available at https://lccn.loc.gov/2016016543

ISBN 9781119149453

A catalogue record for this book is available from the British Library.

Wiley also publishes its books in a variety of electronic formats. Some content that appears in print may not be available in electronic books.

The purpose of this book is to focus on a selection of commonly tested entities, showing low to high power views. Major differences among diagnoses that are sometimes confused are emphasized on Key Differences pages to help train the eye to rapidly notice distinctive features. As a picture is worth a thousand words, text is kept to a minimum. This book should be used as a companion to dermatopathology textbooks and as a pictorial reference/study tool, given that this approach is utilized by the experienced dermatopathologist when constructing examination questions. Often the major distractors are based on gestalt rather than etiology or conventional classifications. It is often the lookalikes that are the most deceptive even though they have no obvious relationship to the correct diagnosis. This book will also be helpful to the dermatopathology novice as it introduces a simple and effective way to approach a slide, and to that end, common diagnoses have been specifically included (i.e. actinic keratosis, basal cell carcinoma).

Dr. James H. Graham, MD, master of dermatopathology and dermatology, who taught me most of what I know.

Ronald J. Barr

Dr. Ronald Barr, Dr. Scott Binder, my dermatopathology colleagues at Yale (Dr. Jennifer McNiff, Dr. Earl Glusac, Dr. Rossitza Lazova, Dr. Shawn Cowper, Dr. Antonio Subtil, Dr. Anjela Galan, Dr. Marcus Bosenberg, and Dr. Peggy Myung), Dr. Jean Bolognia their insights over the years have been invaluable. We also acknowledge the residents at Yale, those in Thailand, and Hadas Skupsky, who rotated with Dr. Barr; all of whom gave constructive feedback on how to improve the atlas for this edition. Thanks are also due to the team at Wiley Blackwell for all their efforts to improve the atlas.

Christine J. Ko

This book is accompanied by a companion website:

www.wiley.com/go/ko/dermatopathology3e

The website includes:

• Interactive multiple choice questions
• PowerPoints of all figures from the book for downloading

Recognizing a disease process on a histopathologic slide becomes instantaneous, with increasing familiarity. Breaking this process down into the how is difficult, especially given that the steps may not be the same for each individual. Nonetheless, on a basic level, it is important to separate a solitary growth (tumor or lesion) from a rash (inflammatory process; (tumor versus rash). For example, clear cell acanthoma can architecturally mimic psoriasis, mycosis fungoides can appear to be a dermatitis, and epithelioid sarcoma can be confused with a palisading granulomatous process.